Barbara Ann Fyffe (Benedict Castle)
(1936 - 2009)
Barbara Ann Fyffe (Benedict Castle)
Nickname: Babs

New York, United States of America
July 6, 1936

Michigan, United States of America
April 23, 2009

Family, Music, friends, writing,golf, photography,

Name: Multiple Myeloma Research Foundation


Description: The Multiple Myeloma Research Foundation (MMRF) was founded in 1998 by identical twin sisters Kathy Giusti and Karen Andrews shortly following Kathy's diagnosis with multiple myeloma. The mission of the MMRF is to urgently and aggressively fund research that will lead to the development of new treatments for multiple myeloma. As the world's number-one funder of multiple myeloma research, the MMRF has raised over $110 million to fund 100 laboratories worldwide. The payback on our investment has been significant: Four new treatments—Thalomid, Velcade, Revlimid and Doxil—approved in four years alone when it usually takes nearly 10 years to bring a single treatment to market. These breakthrough treatments are extending the lives of myeloma patients worldwide and are now being explored in a range of other cancers, including ovarian cancer, breast cancer, prostate cancer, leukemia, and Non-Hodgkin's lymphoma Ten clinical trials of novel and combination treatments facilitated by our sister organization, the Multiple Myeloma Research Consortium (MMRC) 30 MMRF-supported compounds now in pre-clinical studies and clinical trials The MMRF is one of the most effective and efficient organizations of its kind, as evidenced by our exceptional accreditations. In 2007, nearly 93% of every dollar of revenue raised was directed toward myeloma research and related educational programs. The MMRF's approach, with a focus on speed, innovation, and results, is widely recognized across the medical and scientific communities, as well as by several prominent publications, as an optimal model to accelerate medical research and drug development across various cancers and diseases.

Name: Barbara Ann Karmonos Cancer Institude


Description: The Karmanos Advantage When cancer strikes, your first chance is your best chance. And your best chance is at the Barbara Ann Karmanos Cancer Center. Backed by state-of-the-science cancer research conducted right here in Detroit, the Center is the only hospital that focuses solely on cancer in Michigan. Teams of cancer experts diagnose patients with world-class precision and compassionate care. We work with hundreds of doctors to arrange for care convenient for patients and families. Together, our cancer teams and your doctor can recommend the best treatment options with immediate access to the latest cancer-fighting drugs and therapies. Karmanos is designated by the National Cancer Institute as among the very best cancer centers in the United States. It is the preferred hospital for cancer care in southeast Michigan according to the 2007 Cancer Treatment Preference Profile Survey, conducted by the National Research Corporation.. We’ll make sure your first chance at beating cancer is your best chance toward a future free of cancer. So when you or a loved one face cancer, ask your doctor to consult with the Karmanos Cancer Center. Or, make the call yourself at 1-800-KARMANOS. Based in midtown Detroit, Karmanos is one of 40 National Cancer Institute-designated comprehensive cancer centers in the United States. Caring for more than 6,000 new patients annually on a budget of $216 million, conducting more than 700 cancer-specific scientific investigation programs and clinical trials, the Karmanos Cancer Center is among the nation’s best cancer centers. Through the commitment of 1,000 staff, including nearly 300 faculty members, and supported by thousands of volunteer and financial donors, Karmanos strives to prevent, detect and eradicate cancer. Karmanos Mission Statement The Karmanos Cancer Institute is a unique, urban-based integrated center of research, patient care and education, dedicated to the prevention, early detection, treatment and eventual eradication of cancer.



"Mom, Think about you all the time. :) #1"
Greg Castle
March 7th, 2014
"Witnessing the legacy you've left behind is so inspirational. You make me want to be a better person. You will be so missed!"
Alison Matthes
May 11th, 2009
"Mom..the love we share is so precious to me...thank you for this gift...I will hold you next to my heart forever! I love you!"
Kari Castle
May 4th, 2009
"love of divine light may guide you into the eternity."
Sofia Puerta
May 2nd, 2009
"Barb, you had to be the most thoughtful person I have ever known. I have a box full of all the cards, and info. that you thought I might enjoy. You always remembered my B-day, and called me at Houghton Lake, just to see how I was doing."
Linda Cochran
May 1st, 2009
"Precious Barb, my very best forever sister-friend for over 50 years ~ you will always live in my heart and stand beside me ... and we meet again for those great big hugs. I will always love you! Your NU roomie, Sally"
Sally Bermudes
May 1st, 2009


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